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There is strong agreement that HIV prevention should focus o
2019-06-14

There is strong agreement that HIV prevention should focus on approaches that are evidence based, but there is disagreement about how to obtain such rigorous evidence and whether this should refer only to randomised study designs. Pickles and colleagues\' report provides a concrete example of an eff
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br Efforts to address malnutrition maternal and child
2019-06-13

Efforts to address malnutrition, maternal and child mortality, and other global health priorities are heavily reliant on behaviour change, including adoption and correct use of health technology, and following treatment recommendations. One long-standing concern is the limited effectiveness of man
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br More than any other disease group injuries chart
2019-06-13

More than any other disease group, injuries chart the story of a country\'s development in real time. China has seen major changes in injury causes and risks over the past three decades attributable to rapid urbanisation, motorisation, and occupational shifts, as well as health reforms and demogra
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PPCL were associated with a very poor prognosis
2019-06-13

PPCL were associated with a very poor prognosis. The median survival duration according to published small trials was short, ranging from 7 to 13 months, with less than 10% of patients having a median survival of more than 5 years. In the largest recently published epidemiological study, the median
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Causative genes for ARVC and
2019-06-13

Causative genes for ARVC and their respective characteristics are summarized in Table 1. Desmosome genes for ARVC Other causative genes for ARVC Although more than half of ARVC patients carry mutations in desmosome genes, other genes have also been reported as causative genes for ARVC (Table
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In our study of patients
2019-06-13

In our study of 24 patients, we demonstrated the highly accurate identification of PVPs by using the HDMM. These findings aligned with several other studies applying high-density mapping catheters such as either the HDMM or other comparable basket catheters [9–11]. As confirmed by the study group of
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Rulfo emplea un s mil para describir
2019-06-13

Rulfo emplea un símil para describir la caída de Pedro Páramo, para crear el efecto de desmoronamiento del personaje. El lector o la lectora “oyen” la caída de ese cuerpo. Acompañado por una muerta, Damiana Cisneros, que en la posición de Caronte le invita al mundo de los muertos, Pedro Páramo se de
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br Epigenetic regulation of genes
2019-06-13

Epigenetic regulation of genes involved in hepatic lipid metabolism by S1P and SHP The signaling cascade of CBA > S1PR2 > SphK2 > S1P > HDAC1/2 > increased hepatic gene expression can differentially up-regulate blocks of genes involved in the hepatic metabolism of sterols and lipids (Fig. 3, Tabl
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La pregunta que fundamenta esta investigaci n
2019-06-13

La pregunta que fundamenta esta investigación es acerca de la posibilidad de que los participantes de experiencias de acción colectiva urbana definan y re-definan sus pertenencias 5-ht receptors la región y las naciones en las que se insertan. Este acercamiento a las representaciones que los sujetos
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br Conclusion br Conflict of interest br
2019-06-12

Conclusion Conflict of interest Introduction The implantable cardioverter-defibrillator (ICD) has dramatically reduced the risk of sudden death in patients with malignant ventricular tachyarrhythmias [1,2]. However, 10–30% of patients who have undergone ICD implantation experience “electric
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En una clara cr tica al modelo
2019-06-12

En una clara crítica al modelo neoliberal gay importado de Estados Unidos, Néstor Perlongher sostiene que “el gay pasa carboxypeptidase tomarse como modelo de conducta. Este operativo de normalización arroja a los bordes a los nuevos marginados, los excluidos de la fiesta: travestis, locas, chongos,
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br Authorship br Conflict of interest
2019-06-12

Authorship Conflict of interest disclosure Introduction The Aurora kinases are serine/threonine protein kinases essential for regulation of normal toll like receptor mitosis. Aurora kinases A (AAK) and B are overexpressed in hematologic malignancies, including acute myeloid leukemia (AML)
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ryanodine Our results are consistent with previous
2019-06-12

Our results are consistent with previous findings in other malignancies. Functional assays revealed that ectopic expression of UCA1 promoted cell proliferation and/or reduced cell apoptosis in non-small cell lung cancer [19], breast cancer [18], colorectal cancer [28], and renal cell carcinoma [23].
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br Discussion br Conclusions br Conflicts of
2019-06-12

Discussion Conclusions Conflicts of interest Introduction Catecholaminergic polymorphic ventricular tachycardia (CPVT) is induced by emotional stress or exercise in patients without organic heart disease and may be polymorphic or bidirectional (Fig. 1) [1–3]. This ventricular arrhythmia
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Expansion of access to HIV treatment is
2019-06-12

Expansion of access to HIV treatment is a global priority. In July, 2013, UNAIDS, in collaboration with WHO, the Global Fund to fight AIDS, Tuberculosis and Malaria, and the US President\'s Emergency Plan for AIDS Relief (PEPFAR) jointly issued which advocates for a worldwide treatment target of 15
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