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Bmp products such as Fig are persistent pollutants that accu
2019-09-23

Bmp7 products, such as 7–9 (Fig. 2), are persistent pollutants that accumulate in the marine environment and can potentially be transferred to the human population via our trophic connections to the oceans (Wan et al., 2009). In addition to potentially addressing the mechanistic curiosities describe
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Protease Inhibitor Library kinase p Kip is a critical compon
2019-09-23

p27Kip1 is a critical component of the cell cycle machinery [15]. As an inhibitor of cyclin E-Cdk2, p27Kip1 plays a pivotal role in controlling cell proliferation, S-phase entry, and G1-phase exit during development and tumorigenesis [16]. p27Kip1 is predominantly regulated via posttranslational mod
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In this study we observed alterations in mRNA levels
2019-09-23

In this study, we observed alterations in mRNA levels of CRF receptors in the PFCx and Hip during the development of sensitization. In particular, in the Hip both CRF receptors showed significantly increased oxygenase when the sensitization condition was established. Similarly, CRF2 receptor increa
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br Results and discussion br Conclusion
2019-09-23

Results and discussion Conclusion Experimental section Pharmacological studies Introduction Survival analysis is a set of statistical methods that aim at modeling the relationship between a set of predictor variables and an outcome variable and, in particular, prediction of the time w
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br Atypical collagen glycosylation The disaccharide Glc Gal
2019-09-23

Atypical collagen glycosylation The disaccharide Glc(α1-2)Gal(β1-O) decorating collagens is strongly conserved across the animal kingdom, yet for every rule, nature provides exceptions. The deep-sea worm Riftia pachyptila of the phylum Annelida represents an intriguing exception. R. pachyptila is
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Our module is designed to allow
2019-09-23

Our module is designed to allow in-process measurement of [C]-tracer molar activity (MA, GBq/μmol at EOB) using a rock pathway detector with a UV detector at the outlet of the HPLC-portion of the system. In the HPLC chromatogram, peak analysis of the chromatographic data utilized PeakSimple softwar
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Eltanexor br Materials and methods br
2019-09-23

Materials and methods Results Discussion The main finding of the present study is that selective ETA and dual ETA/ETB receptor blockade markedly improve endothelium-dependent vasodilatation in patients with type 2 diabetes and vascular complications. The magnitude of improvement did not dif
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Omar Farha and coworkers have recently successfully employed
2019-09-23

Omar Farha and coworkers have recently successfully employed metal-organic frameworks (MOFs) to tackle these limitations while retaining the essential characteristics of an immobilization material. MOFs consist of metal ions, or small clusters thereof, coordinated with organic ligands. MOFs are high
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br STAR Methods br Acknowledgments We
2019-09-23

STAR★Methods Acknowledgments We would like to thank Dr. Tsung-Ping and Dr. Shang-Yi Tsai, National Institute on Drug Abuse, NIH for sharing protocols on pulse chase experiments and analysis. We would like to thank Dr. William G. Telford for his valuable input on Amnis flow cytometry experiment
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Some antioxidants including N acetylcysteine and SOD have be
2019-09-23

Some antioxidants, including N-acetylcysteine and SOD, have been shown to decrease collagen deposition and protect the lungs in various animal models and even in clinical trials (Chan et al., 2013, Loomis-King et al., 2013, Rafii et al., 2013, Teixeira et al., 2008, Wang et al., 2013). Bleomycin-ind
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We had earlier reported that collagen fibers
2019-09-23

We had earlier reported that collagen fibers with intact native banded structure were occasionally observed in the kinase-deficient, membrane-anchored DDR2 ECD (DDR2/-KD) samples; however, in our DDR1/ECD and DDR2/ECD samples, observation of native banded structure of collagen was far more infrequen
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Phorbol 12,13-dibutyrate clinical There is an increase in sm
2019-09-21

There is an increase in small fruit consumption especially berries in recently. Because small fruits are rich sources of both anthocyanins and phenolic compounds. These chemicals have been found in Vaccinium corymbosum in high levels. Research on small fruits is of vital importance for human nutriti
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Beside the previously reported Topo I inhibition time
2019-09-21

Beside the previously reported Topo I inhibition, time and concentration dependent CRM1 inhibitory properties of klavuzon derivatives have been shown as a second mechanism of action in this work. Especially, compounds 3 and 20 are the most effective derivatives and they completely inhibit CRM1 activ
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Nevertheless of the different types of scoring
2019-09-21

Nevertheless, of the different types of scoring systems so far proposed, each of these [14], [29], [30] considered some aspects that could describe the fibrotic evolution, though none provided a quantitative assessment. Calvaruso et al. [8] showed that CPA had a better histological correlation with
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Daun02 and br Experimental br Results and discussion On the
2019-09-21

Experimental Results and discussion On the basis of the information obtained from the studies on RHA/TiO2 nanocomposites, it Daun02 and is expected that this reagent can be used as a catalyst for the promotion of the organic reactions. So this reagent was used in the promotion of the conversi
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