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br Discussion We evaluated and determined the incidence and
2019-05-07

Discussion We evaluated and determined the incidence and severity of subjective reports of dyspepsia symptoms due to dabigatran. Based on the results of the RE-LY trial [4], the AE that was significantly more common with dabigatran than with warfarin was dyspepsia. In the sub-group (326 Japanese
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Introduction In current rehabilitation practice for most cli
2019-05-07

Introduction In current rehabilitation practice for most clinicians, restorative, supportive and palliative rehabilitation are the primarily courses of treatment for colorectal cancer (CRC) patients in Taiwan. When the end result of treatment for any patient is a fully functional recovery, restorat
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In the current study we first
2019-05-06

In the current study, we first isolated primary HSCs from rat liver and then treated the ciprofloxacin with alcohol. As shown in Fig. 1, the mRNA levels of PCBP2 and type I collagen were increased significantly. In addition, the type I collagen mRNA level was more significantly increased in primary
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Understanding and defining these miRNA profiles helps to
2019-05-06

Understanding and defining these miRNA profiles helps to uncover the clinical usefulness of miRNAs. Numerous human clinical trials are currently evaluating miRNA therapeutics during various liver diseases, such as targeting miR-122 during chronic hepatitis C infection. Aside from therapeutics, the d
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As countries and international platforms engage in post plan
2019-05-06

As countries and international platforms engage in post-2015 planning, now is the time to envision the ending of preventable maternal deaths, as stressed in a recent manifesto for maternal health. The global health ptc124 should build on past successes, and accelerate progress towards elimination o
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Aside from this report only two other
2019-05-06

Aside from this report, only two other studies of dexrazoxane use in adult AML patients have been published. In a series of seven patients with AML, Lemez and Maresova reported that the administration of dexrazoxane 30min before daunorubicin (dose 8-13x higher than daunorubicin) or mitoxantrone (dos
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There are a number of
2019-05-06

There are a number of reasons for this disparity: people with disabilities are disproportionately poor, lacking in access to education and employment, and excluded from social networks. Health-care facilities, equipment, and transportation are often inaccessible. But another significant factor is th
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Epigenetics Compound Library Elderly patients especially tho
2019-05-06

Elderly patients, especially those in excess of 70 years of age, are often quite fragile; such fragility may be secondary to aging or comorbidity. In this “susceptible” patient population, the negative influence of ET-adverse events on patient adherence to a medication regimen can be elevated. This
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Adem s las situaciones en las que Nicol
2019-05-06

Además, las situaciones en las que Nicolás se encuentra con las piedras, sus dudas en torno GDC-0152 si son piedras-huesos o simples piedras, sus caminatas por cerros, encrucijadas y pueblos más o menos fantasmales, las respuestas diferentes a sus preguntas por Pedro Páramo (“¿se acuerda que yo quer
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br Conflict of interest br Introduction Hepatosplenic T
2019-05-05

Conflict of interest Introduction Hepatosplenic T cell lymphoma (HSTCL) is a very rare type of hematologic malignancy, making up about 5% of peripheral T-cell lymphomas. It predominantly affects young male adults, with a higher incidence in patients submitted to immunosuppressive treatment for
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br Discussion Bone marrow fibrosis is known
2019-05-05

Discussion Bone marrow fibrosis is known to be associated with hematolymphoid malignancies such as acute leukemia, Hodgkin and non-Hodgkin lymphoma. Among the acute leukemias, marrow fibrosis is most often seen with acute megakaryoblastic leukemia. It is an uncommon finding in APL and till date o
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Using the finding of a
2019-05-05

Using the finding of a 12% reduction in neonatal mortality, Pitt and colleagues show that, even though the reduction in neonatal mortality was relatively modest, the intervention would still be cost-effective. With further statistical modelling they calculate that such an intervention is likely to b
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Virulence genes were investigated among all beta lactamase p
2019-05-05

Virulence estrogen related receptor were investigated among all beta-lactamase-producing isolates using PCR. There were 54% (n=54) isolates that had one or more than one type of all these six virulence factors. Among all the isolates, 40.74% (n=22) produced OprI (249 bp in size) and 29.62% (n=16) e
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Introduction Neuroblastoma NB which arises
2019-05-05

Introduction Neuroblastoma (NB), which arises from embryonal neural crest cells, is the most common extra-cranial solid tumor of childhood and accounts for more than 15% of all child cancer death [1,2]. Patients with NB frequently manifest disseminated disease at first visit and prognosis of these
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Both breast cancer and MM
2019-05-05

Both breast cancer and MM cause osteolytic lesions, inhibiting osteoblast differentiation and thereby tipping the balance in favour of osteoclastic activity. In contrast, prostate cancer predominantly causes osteoblastic bone disease. Interestingly, increased marrow adiposity has been associated wit
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