• The management of PEComa follows the same treatment

  2019-05-10

  

  The management of PEComa follows the same treatment principles as other subtypes of soft tissue sarcoma. Surgical resection remains the primary treatment modality. There is no consensus on the administration of adjuvant treatment. Other treatment options, including chemotherapy and radiotherapy, hav

• br Introduction Once metastatic breast cancer cells are in t

  2019-05-10

  

  Introduction Once metastatic breast cancer SAR405 manufacturer are in the bone marrow, they hijack signals coming from the normal bone remodelling process and promote bone degradation [1]. Bone degradation is caused by osteoclasts, which have the unique property to dissolve bone mineral and degr

• It is noted that in this study BrS patients had

  2019-05-10

  

  It is noted that in this study BrS patients had an abnormality of plasma K+ concentration which has been suggested to be a potential trigger of Brugada Syndrome episodes [11]. In the absence of renal dysfunction, the hyperkalemia may result from an abnormal phenotype in BrS characterized by mutation

• br Conflict of interest br Introduction

  2019-05-10

  

  Conflict of interest Introduction Over the last several decades, substantial research interest has been focused on characterizing the pathophysiological substrate underlying atrial fibrillation (AF) [1]. AF is a complex arrhythmia and has been shown to be temporally variable, so that AF durati

• A su vez Paraguay expresa claramente en la

  2019-05-10

  

  A su vez, Paraguay expresa claramente en la Ley 3239, Artículo 3, inciso H que se tiende “[…] nuciferine la economía en el uso de los recursos hídricos. a través de su utilización racional y eficiente, posibilitando, así la disponibilidad para otros usos, previendo sobre su derroche, contaminación y

• br A new model of human wellbeing

  2019-05-10

  

  A new model of human wellbeing is emerging to guide humanity in the Anthropocene. In essence, it recognises that wellbeing depends on enabling every person to lead a life of dignity and opportunity, while safeguarding the integrity of Earth\'s life-supporting systems. The conceptual framework of s

• br Discussion The mechanism of

  2019-05-10

  

  Discussion The mechanism of verapamil-sensitive ILVT has been suggested as re-entry with an excitable gap and a slow conduction, because the VT can be induced, entrained, and terminated by programmed ventricular or atrial stimulation [1–6]. In addition, previous studies have suggested that the re

• br Conclusions br Conflict of interest

  2019-05-10

  

  Conclusions Conflict of interest Acknowledgments This study was based in part on data from the National Health Insurance Research Database provided by the Bureau of National Health Insurance, Department of Health and managed by the National Health Research Institutes (registration number 10

• The measurement of the PPI

  2019-05-09

  

  The measurement of the PPI of DP following entrainment pacing usually consists of measuring the interval between the last capturing stimulus and the next DP. This technique is generally based on the assumption that, in the presence of 1:1 capture, pacing depolarizes the zone of slow conduction in th

• br Discussion Treatment of patients with vaginal

  2019-05-09

  

  Discussion Treatment of patients with vaginal leiomyosarcoma is challenging because of the rarity of this disease and a lack of controlled clinical trials comparing management strategies. At this time primary surgery remains the mainstay of management of vaginal leiomyosarcoma. Treatment plans sh

• br Materials and methods br Results br

  2019-05-09

  

  Materials and methods Results Discussion This retrospective analysis examined data from patients with early breast cancer treated over a 12-year period (1997–2009) in a real-world setting. The proportion of patients receiving adjuvant BP therapy dramatically increased during the study perio

• Pellicer alude a esta leyenda varias veces en Oda

  2019-05-09

  

  Pellicer alude salubrinal esta leyenda varias veces en “Oda a Cuauhtémoc”, con imágenes que sugieren la batalla con un astro, la estrella de la aurora de Quetzalcóatl, que en el poema representa un destino fatal: “El arco negro se tendió ante la aurora / y en el último astro fue a clavarse la flecha

• br As the only methods available for dual protection

  2019-05-09

  

  As the only methods available for dual protection against pregnancy and sexually transmitted infections (STIs), male and female condoms have a vital role in sexual and reproductive health. Mags Beksinska and colleagues therefore are to be commended for their randomised crossover trial in this cal

• Well designed operational research is needed to

  2019-05-09

  

  Well designed operational research is needed to refine this starting point. Research is also needed to find out whether prophylactic valganciclovir treatment in high-risk patients might reduce AIDS mortality as well as blindness, as substantial data suggest. WHO leadership is needed to provide cytom

• Efforts to estimate the global burden of typhoid fever can

  2019-05-09

  

  Efforts to estimate the global burden of typhoid fever can be traced to a meeting of the Pan American Health Organization in 1984 and publication of the outcome in 1986. Although an important first step, the 1984 study was recognised as having a number of limitations including provision of scanty me

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