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crm1 In the past decade preclinical studies
2019-04-25

In the past decade, preclinical studies have addressed the putative role of non-coding RNAs in tumorigenesis, metastasis and therapy response in osteotropic cancers. Besides long non-coding RNAs, microRNAs (miRs) represent a class of small non-coding RNAs, (18–25 nucleotides long), that regulate pro
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br In this issue of Tiffany Chao and
2019-04-25

In this issue of , Tiffany Chao and colleagues present a systematic, comprehensive, and critical assessment of published estimates of the cost-effectiveness of essential surgery, and thus make an important contribution to the published work on the economics of global health interventions. Their he
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As for the detection rate we should select a
2019-04-24

As for the detection rate, we should select a different setting in patients with primary prevention and secondary prevention because ICD patients with primary prevention experience the faster lethal arrhythmia with an average rate of 200 beats per minute [27]. On the other hand, ICD recipients with
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Introduction Classically increased cardiac fibrosis has
2019-04-24

Introduction Classically, increased cardiac fibrosis has been shown to be associated with altered cardiac conduction, causing conduction slowing, block, and reentry in studies on isolated animal and diseased human cardiac tissues [1–3]. Interestingly, similar findings were also demonstrated in isol
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La falta de xito del
2019-04-24

La falta de éxito del romance de junto con el fusilamiento, de una manera tan injusta, del héroe, el modelo ciudadano, parece carecer de sentido no solo en términos de la alegoría de fundación sino también en los de la justicia poética. La contradicción aparente de esta carencia de significado ha s
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Monastrol El proyecto literario del conocido escritor mexica
2019-04-23

El proyecto literario del conocido escritor mexicano Ignacio Manuel Altamirano (1834–1893) ha sido ampliamente documentado en los estudios del siglo . Su propósito fue claro: instruir e inspirar al pueblo mexicano, cansado y desilusionado por la situación inestable del México decimonónico y por el s
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br Introdu o Conste que nossa percep o que
2019-04-23

Introdução Conste que nossa percepção é que as noções de reservas, guetos, ou comunidades remanescentes, não dão conta da realidade dessas reivindicações coletivas. Portanto, experiências como as dos Estados Unidos, Haiti, Cuba, República Dominicana, entre outros países com expressivo contingente
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Regarding the expression of NKp NCR Fig A and
2019-04-23

Regarding the expression of NKp46/NCR1 (Fig. 1A and B), both increased and decreased expression are observed depending on patients. Interestingly, the expression of the inducible molecule NKp44/NCR2 is clearly induced in 3 patients (PT1, PT2 and PT5) both regarding the percentage and the MFI. In con
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The IMCI algorithms have been developed and
2019-04-23

The IMCI algorithms have been developed and endorsed by WHO in the 1990s and most low-income and middle-income countries are using them. The IMCI strategy algorithms are not only for diarrhoea but also other common childhood illnesses, such as pneumonia. These countries have invested heavily in trai
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br The UN high level Summit for Refugees and
2019-04-23

The 2016 UN high-level Summit for Refugees and Migrants in New York (NY, USA) provided a historic opportunity to engage world leaders in responding to the health dimensions of mass migration. Despite the magnitude of the phenomenon and its potential for changing global as well as national health p
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herpes simplex virus 1 br Methods This prospective study was
2019-04-23

Methods This prospective study was conducted at the Zekai Tahir Burak Woman\'s Health, Research and Education Hospital, Ankara, Turkey between April 2009 and August 2009. The study was approved by the local Ethics Committee of the hospital, and an informed consent was signed by all patients befor
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Stroke is second only to ischaemic heart
2019-04-22

Stroke is second only to ischaemic gingerol disease as the leading cause of death worldwide; one in six people will have a stroke in their lifetime. , on October 29, reminds us of these striking facts and the need for individuals to know the risk factors. Although the main risk factors for stroke wo
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br Hybrid approach It is still not certain whether a
2019-04-22

Hybrid approach It is still not certain whether a single or a staged approach is safer and more effective. Natale et al. [31] performed a combined closed-chest epicardial monopolar radiofrequency ablation through a transabdominal transdiaphragmatic single port and catheter-based transseptal endoc
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Any abnormality causing a loss of function
2019-04-22

Any abnormality causing a loss-of-function in the IKs macromolecular complex may lead to adrenergic-induced imbalance in ventricular repolarization currents and consequent QTc prolongation, which is identified based on the defective response of IKs to PKA stimuli due to mutations in KCNQ1 (-G269S, -
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buy Octreotide acetate br In Gretchen Stevens and colleagues
2019-04-22

In Gretchen Stevens and colleagues\' update of global, regional, and national trends in haemoglobin concentration and levels of anaemia emphasises both the massive extent of the problem, and its very slow rate of improvement. About 30% or more of women and children younger than 5 years are affecte
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