• Cell migration and invasion are central processes in

  2019-10-07

  

  Cell migration and invasion are central processes in the development and metastasis of cancer. The regulation of cell migration by DDR1 has been reported in many types of cancer cell lines; however, conflicting results have been reported regarding the inhibitory as well as promotive effects of DDR1

• br System description and data collection Fig shows the

  2019-10-07

  

  System description and data collection Fig. 1 shows the arrangement of the system studied. It provided cooling ap4 to maintain thermal conditions in an institutional building. The locations of the measured variables (, and ) relating to temperature and flow rate are indicated in Fig. 1. The elec

• The two SNPs rs rs presented above are part of

  2019-10-07

  

  The two SNPs rs4818-rs4680 presented above are part of the haploblock (rs6269, rs4633, rs4818, rs4680) presenting the 3 major haplotypes which influence the enzymatic activity of COMT. This activity is inversely related to the sensitivity of pain in a chronic pain syndrome; so the haplotype (GCGG) h

• Many studies have found that there is an aberrant DNA

  2019-10-05

  

  Many studies have found that there is an aberrant DNA methylation in the imprinting control region of development-related genes in the spermatozoa of oligozoospermic men (Kobayashi et al, 2007, Marques et al, 2004, Marques et al, 2008), which most likely results from expressional changes in the DNMT

• Although the ferromagnetic particles and T DNA ligase

  2019-10-05

  

  Although the ferromagnetic particles and T4 PAC-1 on the particles were heated by the ac magnetic field, the average temperature of the reaction solution as a whole was kept suitably low for the annealing of DNA ends (16°C). Indeed, no appreciable increase in the temperature of the reaction solution

• br Introduction The stroma associated

  2019-10-05

  

  Introduction The stroma associated with breast cancer metastasis consists of extracellular matrix (ECM) proteins, including fibrillar collagens, and a cellular component comprised of mesenchymal stem/multipotent stromal Nimodipine (MSCs), vessels, and cells of the immune system (Pein and Oskarss

• br Materials and methods br Results and discussion

  2019-10-05

  

  Materials and methods Results and discussion Iron (II)/2-oxoglutarate (2-OG)-dependent oxygenases [28], [29] catalyze oxidative reactions of a range of metabolic processes including the hydroxylation of l-proline and l-lysine residues during the post-translational modification of collagen. Mor

• Emi protein consists of an N

  2019-10-05

  

  Emi2 protein consists of an N-terminal regulatory region and a C-terminal functional region. The C-terminal region contains a destruction box (D-box), which likely competes with APC/C substrates (including cyclin B) for APC/C binding, and a zinc-binding region (ZBR), which somehow inhibits APC/C ubi

• mcc950 Prenylation may turn a flavonoid from an agonist to a

  2019-10-05

  

  Prenylation may turn a flavonoid from an agonist to an antagonist and improve the selectivity to both ERs depending on the position of the substitution. C-8 prenylation appears to promote antagonism to a larger extent than C-6 in ERα due to steric hindrance against generation of agonistic conformati

• Introduction Amphetamine AMPH methamphetamine MA and ethylen

  2019-10-04

  

  Introduction Amphetamine (AMPH), methamphetamine (MA), and 3,4-ethylenedioxymethamphetamine (MDMA) are widely abused psychoactive substances, with the basic chemical structure of phenylethylamine [1]. The abuse of these drugs is associated with psychostimulant, anorectic and hallucinogenic properti

• br Materials and methods br Results and discussion

  2019-10-04

  

  Materials and methods Results and discussion Conclusions Given that the activity of anti-plant virus compounds is related to host tobacco, virus, and compounds, we determined the effect of anti-CMV compound NNM on defense enzyme activity and chlorophyll index in tobacco, and we used RIB as

• br Conclusion In summary a novel and label

  2019-10-04

  

  Conclusion In summary, a novel and label-free fluorescence assay was developed for detection of Cu2+ and galactose oxidase using water-dispersible homogenous alloyed CdZnTeS QDs. The CdZnTeS QDs were firstly synthesized via a simple one-pot hydrothermal route using DMSA as the S source, surface l

• br Materials and methods br Results br Discussion

  2019-10-04

  

  Materials and methods Results Discussion Macrophages and dendritic cells respond to Toll-like receptor (TLR) ligands by upregulating CH25H expression [4], [5]. In the latter cell type TLR-dependent upregulation is mediated via a signalling pathway that involves NFκB and IFNβ secretion and c

• Some family I DNA ligases can use

  2019-10-03

  

  Some family I DNA ligases can use dATP as nucleotide cofactor. For instance, human ZD 7288 I uses dATP with a catalytic efficiency that is only 36-fold lower in comparison to ATP [9]. EhDNAlig is unable to use dATP as a nucleotide cofactor, indicating a more constrained active site in comparison to

• br Materials and methods br Results br Discussion

  2019-10-03

  

  Materials and methods Results Discussion In this work, we have studied the contribution of different pathways to the slow but stable progression of replication forks through DNA damaged by MMS [15]. The in vivo analysis of DNA replication forks along a specific chromosome of S. cerevisiae h

15095 records 918/1007 page Previous Next First page 上5页 916917918919920 下5页 Last page