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The data obtained in our work
2019-04-20
The data obtained in our work showed that AMD was able to inhibit complex I activity and ATP biosynthesis in MRC-5 cells. These effects were accompanied by an increase in lipid and protein oxidative damage and a decrease in NO levels and superoxide dismutase and catalase activities, suggesting that
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br Escribir y destacar promoci n la identidad por
2019-04-20
Escribir y destacar (promoción 1975-1985): la identidad por las diferencias ¿Cómo escribir dentro de un mercado de tantos competidores para un país de escasos lectores? En México, ni siquiera los estudiantes de la universidad consumen libros y hay más papelerías que librerías (Zaid 2013: 143-154
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purchase SB202190 Vaccinated individuals might represent a s
2019-04-20
Vaccinated individuals might represent a safer source of hyperimmune serum. Two vaccine candidates will be tested soon in west Africa. If serum from vaccinated individuals has neutralising activity against the virus in cell models, this serum could be used as adjuvant therapy for EVD. In parallel, a
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Undoubtedly hydroxyurea has a huge potential
2019-04-20
Undoubtedly, hydroxyurea has a huge potential for improving the quality of lives of people affected by sickle-cell anaemia in settings where frequent and probably unsafe blood transfusions are the current standard of care. However, attention needs to be directed towards the potential adverse effects
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En ese encuentro de intereses entre
2019-04-20
En ese encuentro de intereses entre los distintos grupos, bien sea por dominar el territorio, o por imponer la fuerza, o bien por controlar el negocio del narcotráfico, la población queda expuesta y vulnerable. Los ataques entre unos y otros tienen serias repercusiones sobre los poblados “las accion
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Introduction Acute erythroleukemia AEL is a rare
2019-04-20
Introduction Acute erythroleukemia (AEL) is a rare subtype of acute myeloid leukemia (AML), accounting for 3–5% of all AML cases. It is characterized by the expansion of erythroblasts in the bone marrow (BM). Its clinical presentation often resembles myelodysplastic syndromes (MDS), both in terms o
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No livro de fato a
2019-04-19
No livro, de fato, resperidone aproximação aparece muito mais como uma metáfora do que como um tratado. Tudo parece girar em torno da palavra intuição ou de uma ideia de sensação. Algo a ver com o inexplicável. “ por que, ao entrar no quarto onde esse homem passa seus dias recluso [o homem imóvel],
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br Case report A year old man was diagnosed with
2019-04-19
Case report A 73 year-old man was diagnosed with chronic lymphocytic lymphoma (CLL) in December 2009, where he presented with a servical mass at another state hospital. He was treated with 6 cycles of cyclophosphamide, vincristine and prednisone (CVP). On follow-up he received 6 cycles of fludara
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The study by Mijiti and colleagues
2019-04-19
The study by Mijiti and colleagues also illustrates that, besides medical factors, social determinants of health—poverty, education, geography, customs, etc—also play an important role in tuberculosis control. Owing to the low socioeconomic status and poor social health environment, tuberculosis mai
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br The Millennium Development Goals on health have expanded
2019-04-19
The Millennium Development Goals on health have expanded access to basic health interventions to millions of people in low-income and middle-income countries (LMICs). However, access alone will not be sufficient to meet the Sustainable Development Goals (SDGs) if health systems cannot provide hig
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Therefore the current study was designed to
2019-04-19
Therefore, the current study was designed to investigate the effect of LS on coagulopathy and organ dysfunction in rats with endotoxemia induced by LPS, and to explore possible pathophysiological mechanisms. Previous studies have demonstrated that thromboelastography (TEG) appears to be a reliable m
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br Radiotherapy for bone metastases As a palliative
2019-04-19
Radiotherapy for bone metastases As a palliative intervention, radiotherapy is effective and efficient at treating painful bone metastases, and the side effects associated with its use are manageable and usually self-limiting in nature. Between 50% and 80% of patients gain at least partial relief
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Editorial opinion piece Many patients with advanced cancer w
2019-04-19
Editorial/opinion piece Many patients with advanced cancer will develop bone metastases and associated complications, including severe pain and debilitating skeletal-related events (SREs), which require radiotherapy, surgery or changes to antineoplastic regimens [1–3]. Fortunately, there are effect
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br Introduction Magnetic resonance imaging MRI
2019-04-19
Introduction Magnetic resonance imaging (MRI) has great utility in evaluating musculoskeletal tumors. However, some lesions have an appearance on MRI that make it challenging to differentiate benign from malignant lesions. Even intravenous (IV) melanin sometimes does not allow differentiation of
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Certainly dynamic interactions between DTCs and stromal
2019-04-19
Certainly, dynamic interactions between DTCs and stromal hepititis b within the bone microenvironment disrupt bone homeostasis, which is normally tightly controlled, to fuel metastatic progression [18] (Table 1). For example, it is well established that osteolytic breast cancer DTC-derived factors,
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